Dr. Heinz Doofenshmirtz, is the main villain from Phineas and Ferb; he is a mad scientist and head of Doofenshmirtz Evil Incorporated. He tends not to be evil in the traditional sense, but rather overly dramatic, eccentric and generally clueless. He constantly attempts to wreak havoc across "the entire Tri-State Area", but all of his plans tend to be thwarted by Perry the Platypus.

In the series' Christmas special, Phineas and Ferb Christmas Vacation!, he plots to ruin Christmas for the rest of Danville by convincing Santa Claus that everyone in the city is naughty, using his newest device, the Naughtyinator. However, the flaw in his plan is that he doesn't hate Christmas like most other villains.

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