Lois Patrice Griffin (née Pewterschmidt) is the wife of Peter Griffin and mother of Meg, Chris and Stewie Griffin. Lois lives at 31 Spooner Street with her family and also Brian, the anthropomorphic family dog. In the first Christmas special, Lois is full of Christmas spirits when she sees the star on the town's Christmas tree and thinks about the joy and wonders until Meg points they are "out of paper towels"; Lois gets enraged and goes to the Christmas tree to remove the star, believing it "lied" to her. However, Peter hosts the Christmas pageant, while Stewie is the Baby Savior, to calm Lois down. After Lois sees Stewie is performing, she went back to normal and returned the star. Joe shoots her with an elephant bullet tart to tranquilize her. On Christmas morning, Lois is still paralyzed from the elephant bullet tart.
Appearances in Christmas specials
- "A Very Special Family Guy Freakin' Christmas"
- "Road to the North Pole"
- "Jesus, Mary and Joseph!"
- "Christmas Guy"
- "The 2000-Year-Old Virgin"
- "How the Griffin Stole Christmas"
- "Don't Be a Dickens At Christmas"
- "Christmas is Coming"